Ian Swanson California Institute of Technology Ian Swanson: Tangled Physics: Superstring Theory and the AdS/CFT Conjecture on: Caltech Ian Swanson, a graduate student in physics at Caltech, discusses the quantum field theory is known as the Standard Model of particle physics, providing the most accurate physical predictions in the history of science. Physicists must now unite the Standard Model with the tenets of general relativity, and string theory is arguably the most promising candidate of the last 50 years.
Interview on: The Vega Science Trust Max Perutz discovered the structure of Haemoglobin (Nobel Prize 1962) and was the founder of the Laboratory for Molecular Biology in Cambridge, the birth place of modern molecular biology.
Donald S. Cohen California Institute of Technology Diffusion-Mediated Regulation In Endocrine Cell Networks on: Caltech Donald S. Cohen, Charles Lee Powell Professor of Applied Mathematics, Emeritus, Caltech; Danny Petrasek, Senior Research Fellow, Applied and Computational Mathematics, Caltech; and William Goodman, Professor of Medicine, UCLA, presented this lecture as part of the 0.1 Seminar series. They discuss a computational model that demonstrates diffusion-mediated regulation and that shows qualitative agreement with published experimental results. Such a signaling mechanism may regulate other networks with similar biochemical and geometric properties.
David Wild Keck Graduate Insitute Reconstructing Transcriptional Networks using Bayesian State Space Model on: A major challenge in systems biology is the ability to model complex regulatory interactions. In previous work, we have used Linear-Gaussian state-space models (SSMs), also known as Linear Dynamical Systems (LDS) or Kalman filter models to 'reverse-engineer' regulatory networks from high-throughput data sources, such as microarray gene expression profiling. SSM models are a subclass of dynamic Bayesian networks used for modeling time series data and have been used extensively in many areas of control and signal processing. The parameters of an SSM can be learned using maximum likelihood (ML) methods. However, in general the ML approach is prone to overfitting, especially when fitting models with many variables with relatively small amounts of data. We have instead turned to a fully Bayesian analysis, which avoids overfitting and provides error bars on all model parameters ?
Brian Greene Columbia University Charlie Rose - A Discussion About Science on: Google Video Segment 1: A conversation about the public understanding of science with: Guest Host Sir Paul Nurse, President, The Rockefeller University, physicist Brian Greene, and actor Alan Alda.
Nicholas Negroponte Massachusetts Institute of Technology The future of computing on: TEDtalks Nicholas Negroponte is former Director of the MIT Media Lab, and founder of the non-profit, One Laptop Per Child. (Recorded February 2006 in Monterey, CA. Duration: 18:21
35th Anniversary of the Intel(r) 4004 Microprocessor on: The Computer History Museum and the Intel Museum invite you to mark the 35th anniversary of one of the most important products in technology history. Introduced in November 1971, the Intel(r) 4004 microprocessor was an early and significant commercial product to embody computer architecture within a silicon device. And it started an electronics revolution that changed our world.
Charles Mayo Center for Coastal Studies The Whales of Stellwagen Through Compound Eyes on: WBGH Dr. Mayo describes the interrelationship of human endeavors and the life patterns of whales within the Stellwagen Bank National Marine Sanctuary.
Christof Koch California Institute of Technology CNS/Bi 120. The Neuronal Basis of Consciousness on: Caltech During the spring 2003 term Dr. Koch, the Troendle Professor of Cognitive and Behavioral Biology and professor of computation and neural systems at Caltech, recorded this course, which discusses what are the correlates of consciousness in the brain, and which provides a framework for addressing this question, using a reductionist point of view.
Martin Adelman George Washington University Workshop 4: Compensation and Compulsory Licenses on: World Bank Two panels: in the first, F.M. Scherer from Princeton University addresses the economics of compulsory drug patent licensing, followed by Jerome Reichman from Duke University who provided an overview of his recent research for UNCTAD on US and Canadian experiences with compulsory licensing.
E. O. Wilson Harvard University E. O. Wilson on Charlie Rose: Fundamental Unity between Knowledge Fields on: Google Video In the third segment of this broadcast, a discussion with biologist E.O. Wilson of Harvard about his work in pioneering the fields of sociobiology and biodiversity and his Pulitzer-prize winning science books. He argues that there should be fundamental unity between all fields of human knowledge.
Living with a Star-an encounter with Robert Walsh on: sciencelive Currently Robert is a Senior Lecturer in Astrophysics and Mathematics at the University of Central Lancashire, Preston, UK. His area of research is Solar Physics, where he uses space-based solar observatories (solar observing satellites) to monitor our closest star and then set-up sophisticated super-computer simulations to try and reproduce what we observe. He is married to Heather and has two children, Matthew (aged three) and Emma (aged 6 weeks).
Daniel Masys University of California, San Diego Medical Informatics 1: Principles of Database Design on: Woods Hole Oceanographic Institution Medical Informatics is the science of organizing information to make it useful, to make it retrievable, so people can use it to solve health problems and understand health and disease better. It is the technology for implementing that science, such as databases, communication networks, and other forms of digital tools.
Lessons from Hurricane Katrina: Can We Save California's Delta? on: UC Berkeley Webcasts Professor Ray Seed co-chairs the joint State-Federal Technical Advisory Committee for assessment of levee-related risk for the State of California. Professor Seed also led the post-Katrina investigation, and will present his team's analysis of what went wrong and how we in California can learn from these mistakes.
Cosmic Inflation and the Accelerating Universe- Alan H. Guth on: National Science Foundation Dr. Guth describes the theory of inflation and presents evidence that indicates our universe very likely underwent a perod of exponential doubling in size in its early existence. He also discusses the surprising observation that the enormous expansion of the universe is accelerating, offers possible explanations for this acceleration, and describes its impact on particle physics.
Roy Gould Harvard Smithsonian Center for Astrophysics Who Needs Physics? on: WGBH Forum Physics - the field that underlies every other field of science, from archaeology (think carbon dating) to virology (think electron microscopes). How will physics help reveal the true nature of the cosmos?
Briefing: Documenting Endangered Languages on: National Science Foundation Linguistics experts estimate that almost half of the world's 6,000-7,000 existing languages--and the cultural, linguistic and cognitive information they encapsulate--are headed for oblivion. The National Science Foundation, in partnership with the National Endowment for the Humanities, has launched a multi-year 'rescue mission' to document and preserve key languages before they become extinct. More than 70 at-risk languages will be digitally archived as part of the new Documenting Endangered Languages (DEL) program.
Richard Axel Columbia University Interview on: Nobelprize.org Richard Axel and Linda B. Buck, December 11, 2004. Interviewer is Peter Sylwan, science writer. The Laureates talk about the big event of the Prize Award Ceremony, the genomes of the nose (1:40), the importance of the sensor organ (3:25), the smell of emotions (10:23), the mapping out of the molecules of sense inside the brain (14:36) and challenges for neuroscience in the future (18:22)
Kip Thorne California Institute of Technology Ph237. Gravitational Waves on: Caltech During the winter and spring 2002 terms Dr. Thorne, Richard P. Feynman Professor of Theoretical Physics at Caltech, and his guest speakers recorded this course, which discusses the theory of gravitational waves. (If you are a speaker in these lectures and do not wish to have your lecture broadcasted, or wish to send a Notice of Alleged Copyright Infringement, please contact our Designated Agent.
Julia A. Kornfield California Institute of Technology Unsolved Problems In Biomedical Materials Engineering on: Caltech Dr. Julia A. Kornfield, Associate Professor of Chemical Engineering at Caltech, and Dr. David A. Tirrell, Ross McCollum-William H. Corcoran Professor of Chemistry and Chemical Engineering at Caltech, presented this lecture as part of the 0.1 Seminar series. They discuss some of the complications and challenges that arise in the clinical use of medical devices that are surgically implanted each year, and present some current approaches to the amelioration of the resulting problems.